kratom - Eine Übersicht
kratom - Eine Übersicht
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25 More research is needed to better understand the impact of using kratom hinein combination with other substances. (See Is kratom safe?)
NIDA is a biomedical research organization and does not provide personalized medical advice, treatment, counseling, or legal consultation. Information provided by NIDA is not a substitute for professional medical care or legal consultation.
While research is underway to explore possible therapeutic benefits (Tümpel Could kratom Beryllium used as medicine?), kratom products have not been demonstrated to Beryllium safe and effective for any medical condition. Of Beurteilung, safe and effective medications are approved to help control withdrawal symptoms and cravings associated with opioid use disorder, as well as other substance use disorders.
While there are no uses for kratom approved by the U.S. Food and Drug Administration, people report using kratom to manage drug withdrawal symptoms and cravings (especially related to opioid use), pain, fatigue and mental health problems.
They noted that 11 people had been hospitalized with salmonella illness linked to kratom. Those Weltgesundheitsorganisation fell ill consumed kratom in pills, powder or tea.
NIDA and its partners conduct and support research evaluating kratom and related compounds as potential treatments for chronic pain and for opioid withdrawal here and opioid use disorder. Learn more: How is NIDA advancing research on kratom?
In cultures where the plant grows, kratom has been used hinein traditional medicine.[9] The leaves are chewed to relieve musculoskeletal pain and increase energy, appetite, and sexual desire rein ways similar to khat and coca.
NIDA also supports research towards better understanding the health and safety effects of kratom use. Rare but serious effects have been reported rein people who use kratom, including psychiatric, cardiovascular, gastrointestinal and respiratory problems.
Kratom overdose is a subject of concern rein many countries because of the associated rising number of hospitalizations and deaths in which chronic kratom use is a contributing factor.[12][17] According to clinical reviews, a kratom overdose can cause liver toxicity, seizures, coma, and death,[17] especially hinein combination with excessive alcohol use.
Kratom, due to its opioid-like action, has been used for treatment of pain and opioid withdrawal. Animal studies suggest that the primary mitragynine pharmacologic action occurs at the mu
Most of the psychoactive effects of kratom have evolved from anecdotal and case reports. Kratom has an unusual action of producing both stimulant effects at lower doses and more CNS depressant side effects at higher doses.
Of particular interest to NIDA, early studies suggest kratom and kratom compounds warrant further study as experimental treatments for substance use disorders, specifically opioid use disorder.9, 48 Such treatments are urgently needed to help curb the drug overdose epidemic rein the United States.
According to the FDA, deaths with kratom use have occurred, the scientific literature has disclosed serious concerns regarding the toxicity of kratom in multiple organ systems, and kratom affects the same opioid receptors as morphine.
While withdrawal and substance use disorder symptoms related to kratom use have not been extensively studied, some people who use kratom report experiencing them.1, 3, 9 (See Is kratom addictive? Do people experience kratom withdrawal?) There are currently no approved medical therapies for these conditions.
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